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Biology And Life Sciences PDF Available DOI: 10.1038/nmeth.2929 Non-peer-reviewed Preprint

Efficient Bayesian-based Multi-View Deconvolution

Abstract

Light sheet fluorescence microscopy is able to image large specimen with high resolution by imaging the sam- ples from multiple angles. Multi-view deconvolution can significantly improve the resolution and contrast of the images, but its application has been limited due to the large size of the datasets. Here we present a Bayesian- based derivation of multi-view deconvolution that drastically improves the convergence time and provide a fast implementation utilizing graphics hardware.
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