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Showing 1605 results for "f. hoffmann" · Peer-Reviewed
Multidisciplinary & Other Peer-Reviewed PDF DOI

Multiscale Anisotropic Morphological Directional Derivatives for Noise-Robust Image Edge Detection

Xiaohang Yu, Xinyu Wang, Jie Liu, Rongrong Xie, Yunhong Li · 2022

Different types of noise interference lead to low accuracy of image edge detection and severe loss of feature extraction details. A new noise-robust edge detection method is proposed, which uses a set…

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Medicine & Health Peer-Reviewed PDF DOI

High-Flow Nasal Cannula Therapy in COVID-19: Using the ROX Index to Predict Success.

Abhimanyu Chandel, Saloni Patolia, A Whitney Brown, A Claire Collins, Dhwani Sahjwani, Vikramjit Khangoora, Paula C Cameron, Mehul Desai, Aditya Kasarabada, Jack K Kilcullen, Steven D Nathan, Christopher S King · 2021

Optimal timing of mechanical ventilation in COVID-19 is uncertain. We sought to evaluate outcomes of delayed intubation and examine the ROX index (ie, [S pO 2 /F IO 2 ]/breathing frequency) to predict…

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Medicine & Health Peer-Reviewed PDF DOI

Impact of COVID-19 Pandemic on the outcomes in patients with Critical Limb Threatening Ischaemia and Diabetic Foot Infection.

Mustafa Musajee, Hany Zayed, Narayanan Thulasidasan, Mohamed Sayed, Federica Francia, Meryl Green, Martin Arissol, Alpa Lakhani, Lukla Biasi, Sanjay Patel · 2021

Examine the impact of Coronavirus-2019(COVID-19) pandemic on the outcomes in patients with critical limb threatening ischemia(CLTI) or diabetic foot infection(DFI). Patients with CLTI and/or DFI are a…

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Medicine & Health Peer-Reviewed PDF DOI

High-flow therapy: physiological effects and clinical applications.

Rebecca F D'Cruz, Nicholas Hart, Georgios Kaltsakas · 2021

Humidified high-flow therapy (HFT) is a noninvasive respiratory therapy, typically delivered through a nasal cannula interface, which delivers a stable fraction of inspired oxygen ( F IO 2 ) at flow r…

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Medicine & Health Peer-Reviewed PDF DOI

Dysmagnesemia in Covid-19 cohort patients: prevalence and associated factors.

Didier Quilliot, Olivier Bonsack, Roland Jaussaud, Andre Mazur · 2021

Hypomagnesemia and hypermagnesemia could have serious implications and possibly lead to progress from a mild form to a severe outcome of Covid-19. Susceptibility of subjects with low magnesium status …

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Medicine & Health Peer-Reviewed PDF DOI

Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational study.

Rana H Refaey, Mohamed K El-Ashrey, Yassin M Nissan · 2021

The COVID-19 pandemic has urged for the repurposing of existing drugs for rapid management and treatment. Renin inhibitors down regulation of ACE2, which is an essential receptor for SARS-CoV-2 infect…

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Medicine & Health Peer-Reviewed PDF DOI

Von Willebrand factor propeptide in severe coronavirus disease 2019 (COVID-19): evidence of acute and sustained endothelial cell activation.

Soracha E Ward, Gerard F Curley, Michelle Lavin, Helen Fogarty, Ellie Karampini, Natalie L McEvoy, Jennifer Clarke, Maria Boylan, Razi Alalqam, Amy P Worrall, Claire Kelly, Eoghan de Barra, Siobhan Glavey, Cliona Ni Cheallaigh, Colm Bergin, Ignacio Martin-Loeches, Liam Townsend, Patrick W Mallon, Jamie M O'Sullivan, James S O'Donnell · 2021

Endothelial cell (EC) activation plays a key role in the pathogenesis of pulmonary microvascular occlusion, which is a hallmark of severe coronavirus disease 2019 (COVID-19). Consistent with EC activa…

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Medicine & Health Peer-Reviewed PDF DOI

Is Guillain-Barrè syndrome triggered by SARS-CoV-2? Case report and literature review.

Edoardo Agosti, Andrea Giorgianni, Francesco D'Amore, Gabriele Vinacci, Sergio Balbi, Davide Locatelli · 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the infectious agent responsible for coronavirus disease 2019 (COVID-19). Respiratory and gastrointestinal manifestations of SARS-CoV-2 …

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Medicine & Health Peer-Reviewed PDF DOI

Clinical outcomes of COVID-19 in hemodialysis patients in the city of Zonguldak, Turkey.

Mahmud Islam, Yasin Ozturk, Yener Koc · 2021

Patients on maintenance hemodialysis are vulnerable to viral infections like COVID-19 because of the low chance of obedience and complying with rules besides the need for transfer to distant dialysis …

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Medicine & Health Peer-Reviewed PDF DOI

Inflammatory response in lungs and extrapulmonary sites detected by [F] fluorodeoxyglucose PET/CT in convalescing COVID-19 patients tested negative for coronavirus.

Yan Bai, Junling Xu, Lijuan Chen, Chang Fu, Yi Kang, Weifeng Zhang, Georges Ei Fakhri, Jianqin Gu, Fengmin Shao, Meiyun Wang · 2021

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in an ongoing global pandemic of coronavirus disease 2019 (COVID-19). The challenges associated with imaging infected pati…

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Medicine & Health Peer-Reviewed PDF DOI

Assessment of Awareness and Knowledge on Novel Coronavirus (COVID-19) Pandemic among Seafarers.

Gopi Battineni, Getu Gamo Sagaro, Nalini Chintalapudi, Marzio Di Canio, Francesco Amenta · 2021

Background : The ongoing pandemic due to the novel coronavirus (COVID-19) is becoming a serious global threat. Experts suggest that the infection can be controlled by immediate prevention measures. Sa…

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Medicine & Health Peer-Reviewed PDF DOI

Phytotherapeutic options for the treatment of COVID-19: A concise viewpoint.

nan · 2021

Retraction: Din, M., Ali, F., Waris, A., Zia, F., & Ali, M. Phytotherapeutic options for the treatment of COVID-19: A concise viewpoint. Phytotherapy Research; 2020, Volume 34, Issue 7, pages 1469-147…

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Medicine & Health Peer-Reviewed PDF DOI

Psychological impact of the COVID-19 pandemic on healthcare workers in India: An observational study.

Rachna Raj, Soujanya Koyalada, Amit Kumar, Stuti Kumari, Pooja Pani, Nishant, Kishore Kumar Singh · 2021

The World Health Organization (WHO) in January 2020 declared outbreak of novel coronavirus disease, COVID-19, an international public health emergency. It was stated that there was high COVID-19 sprea…

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Medicine & Health Peer-Reviewed PDF DOI

Benefits of early aggressive immunomodulatory therapy (tocilizumab and methylprednisolone) in COVID-19: Single center cohort study of 685 patients.

Buzon-Martin Luis, Montero-Baladia Miguel, Delgado-Lopez Pedro, Iglesias-Posadilla David, Astigarraga Itziar, Galacho-Harriero Ana, Iglesias-Julian Enrique, Lopez-Veloso Maria, De La Torre-Ferrera Noelia, Barraza-Bengoechea Julio Cesar, Ubeira-Iglesias Marta, San Llorente-Sebastian Rodrigo, Colazo-Burlato Maria, Lorenzo-Martin Andres, Minguito de la Iglesia Javier, Garcia-Munoz Juan Pablo, Hermida-Fernandez Gerardo, Navarro-San Francisco Carolina, Boado-Lama Jorge, Fernandez-Regueras Maria, Callejo-Torre Fernando, Ossa-Echeverri Sergio, Fisac-Cuadrado Lourdes, Gero-Escapa Maria, Megias-Lobon Gregoria, Simon-Rodriguez Adolfo, Fernandez-Ratero Jose Antonio · 2021

A growing evidence suggests that immune dysregulation and thrombotic phenomena are key features in the pathophysiology of COVID-19. Apart from antivirals and respiratory support, anticoagulants, corti…

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Medicine & Health Peer-Reviewed PDF DOI

Global stability analysis of the role of multi-therapies and non-pharmaceutical treatment protocols for COVID-19 pandemic.

Bassey Echeng Bassey, Jeremiah U Atsu · 2021

In this paper, we sought and presented an 8-Dimensional deterministic mathematical COVID-19 dynamic model that accounted for the global stability analysis of the role of dual-bilinear treatment protoc…

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Medicine & Health Peer-Reviewed PDF DOI

Optimal use of tocilizumab for severe and critical COVID-19: a systematic review and meta-analysis.

Cahyo Wibisono Nugroho, Satriyo Dwi Suryantoro, Yuliasih Yuliasih, Alfian Nur Rosyid, Tri Pudy Asmarawati, Lucky Andrianto, Herley Windo Setiawan, Bagus Aulia Mahdi, Choirina Windradi, Esthiningrum Dewi Agustin, Jonny Karunia Fajar · 2021

Background: Several studies have revealed the potential use of tocilizumab in treating COVID-19 since no therapy has yet been approved for COVID-19 pneumonia. Tocilizumab may provide clinical benefits…

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Medicine & Health Peer-Reviewed PDF DOI

Efficacy of therapeutic plasma exchange in the treatment of penn class 3 and 4 cytokine release syndrome complicating COVID-19.

W Larry Gluck, Sean P Callahan, Robert A Brevetta, Antine E Stenbit, Wesley M Smith, Julie C Martin, Anna V Blenda, Sergio Arce, W Jeffery Edenfield · 2021

Cytokine release syndrome (CRS) is a potentially severe complication of COVID-19 most commonly resulting in respiratory failure. This ten-patient study was designed to determine the efficacy of therap…

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Medicine & Health Peer-Reviewed PDF DOI

Risk Factors of Mortality for Patients Receiving Venovenous Extracorporeal Membrane Oxygenation for COVID-19 Acute Respiratory Distress Syndrome.

Zachary R Bergman, Jillian K Wothe, Fatima S Alwan, Arianna E Lofrano, Kelly M Tointon, Melissa Doucette, John K Bohman, Ramiro Saavedra-Romero, Matthew E Prekker, Elizabeth R Lusczek, Greg Beilman, Melissa E Brunsvold · 2021

Background: Venovenous extracorporeal membrane oxygenation (VV-ECMO) for select adults with severe acute respiratory distress syndrome (ARDS) cause by coronavirus disease 2019 (COVID-19) infection is …

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Medicine & Health Peer-Reviewed PDF DOI

Influence of individual, illness and environmental factors on place of death among people with neurodegenerative diseases: a retrospective, observational, comparative cohort study.

Richard Nicholas, Emma Nicholas, Mike Hannides, Vishal Gautam, Tim Friede, Jonathan Koffman · 2021

In long-term neurological conditions, location of death is poorly understood but is seen as a marker of quality of dying. To examine individual, illness and environmental factors on place of death amo…

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Medicine & Health Peer-Reviewed PDF DOI

Descriptive Norms and Prototypes Predict COVID-19 Prevention Cognitions and Behaviors in the United States: Applying the Prototype Willingness Model to Pandemic Mitigation.

Laurel M Peterson, Marie Helweg-Larsen, Sarah DiMuccio · 2021

Early in the COVID-19 pandemic, prevention behavior adoption occurred in a rapidly changing context. In contrast to expectancy-value theories, the Prototype Willingness Model (PWM) is well-suited for …

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