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Showing 2142 results for "immunological" · Peer-Reviewed
Medicine & Health Peer-Reviewed PDF DOI

Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection.

Alberto Perez-Gomez, Joana Vitalle, Carmen Gasca-Capote, Alicia Gutierrez-Valencia, Maria Trujillo-Rodriguez, Ana Serna-Gallego, Esperanza Munoz-Muela, Maria de Los Reyes Jimenez-Leon, Mohamed Rafii-El-Idrissi Benhnia, Inmaculada Rivas-Jeremias, Cesar Sotomayor, Cristina Roca-Oporto, Nuria Espinosa, Carmen Infante-Dominguez, Juan Carlos Crespo-Rivas, Alberto Fernandez-Villar, Alexandre Perez-Gonzalez, Luis Fernando Lopez-Cortes, Eva Poveda, Ezequiel Ruiz-Mateos · 2021

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense agai…

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Medicine & Health Peer-Reviewed PDF DOI

Characterisation of a novel ACE2-based therapeutic with enhanced rather than reduced activity against SARS-CoV-2 variants.

Mathieu Ferrari, Leila Mekkaoui, F Tudor Ilca, Zulaikha Akbar, Reyisa Bughda, Katarina Lamb, Katarzyna Ward, Farhaan Parekh, Rajeev Karattil, Christopher Allen, Philip Wu, Vania Baldan, Giada Mattiuzzo, Emma M Bentley, Yasuhiro Takeuchi, James Sillibourne, Preeta Datta, Alexander Kinna, Martin Pule, Shimobi C Onuoha · 2021

The human angiotensin-converting enzyme 2 acts as the host cell receptor for SARS-CoV-2 and the other members of the Coronaviridae family SARS-CoV-1 and HCoV-NL63. Here we report the biophysical prope…

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Medicine & Health Peer-Reviewed PDF DOI

COVID-19 age-dependent immunology and clinical outcomes: implications for vaccines.

Azza Sarfraz, Saman Hasan Siddiqui, Junaid Iqbal, Syed Asad Ali, Zahra Hasan, Zouina Sarfraz, Najeeha Talat Iqbal · 2021

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leading to acute respiratory distress syndrome (ARDS). Understanding the evolution of the …

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Medicine & Health Peer-Reviewed PDF DOI

Immunomodulation as a Potent COVID-19 Pharmacotherapy: Past, Present and Future.

Decsa Medika Hertanto, Bayu Satria Wiratama, Henry Sutanto, Citrawati Dyah Kencono Wungu · 2021

In the first year of its appearance, the 2019 coronavirus disease (COVID-19) has affected more than 150 million individuals and killed 3 million people worldwide. The pandemic has also triggered numer…

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Medicine & Health Peer-Reviewed PDF DOI

Adversity in early life and pregnancy are immunologically distinct from total life adversity: macrophage-associated phenotypes in women exposed to interpersonal violence.

Kirstin Aschbacher, Melissa Hagan, Iris M Steine, Luisa Rivera, Steve Cole, Alyssa Baccarella, Elissa S Epel, Alicia Lieberman, Nicole R Bush · 2021

Early childhood and pregnancy are two sensitive periods of heightened immune plasticity, when exposure to adversity may disproportionately increase health risks. However, we need deeper phenotyping to…

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Medicine & Health Peer-Reviewed PDF DOI

Role of Laboratory Medicine in SARS-CoV-2 Diagnostics. Lessons Learned from a Pandemic.

Irena Dus-Ilnicka, Aleksander Szymczak, Malgorzata Malodobra-Mazur, Miron Tokarski · 2021

Since the 2019 novel coronavirus outbreak began in Wuhan, China, diagnostic methods in the field of molecular biology have been developing faster than ever under the vigilant eye of world's research c…

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Medicine & Health Peer-Reviewed PDF DOI

Attenuation of clinical and immunological outcomes during SARS-CoV-2 infection by ivermectin.

Guilherme Dias de Melo, Francoise Lazarini, Florence Larrous, Lena Feige, Etienne Kornobis, Sylvain Levallois, Agnes Marchio, Lauriane Kergoat, David Hardy, Thomas Cokelaer, Pascal Pineau, Marc Lecuit, Pierre-Marie Lledo, Jean-Pierre Changeux, Herve Bourhy · 2021

The devastating pandemic due to SARS-CoV-2 and the emergence of antigenic variants that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive understanding of the patho…

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Medicine & Health Peer-Reviewed PDF DOI

SARS-CoV-2 spike linear epitope scanning via a peptide microarray through sera profiling.

Yang Li, Dan-Yun Lai, Sheng-Ce Tao · 2021

Host humoral immunological response plays an essential role in protection against pathogens. Identification of B-cell epitopes on antigens is required for accurate diagnosis and vaccine development. T…

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Medicine & Health Peer-Reviewed PDF DOI

Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial.

Alberto M Borobia, Antonio J Carcas, Mayte Perez-Olmeda, Luis Castano, Maria Jesus Bertran, Javier Garcia-Perez, Magdalena Campins, Antonio Portoles, Maria Gonzalez-Perez, Maria Teresa Garcia Morales, Eunate Arana-Arri, Marta Aldea, Francisco Diez-Fuertes, Inmaculada Fuentes, Ana Ascaso, David Lora, Natale Imaz-Ayo, Lourdes E Baron-Mira, Antonia Agusti, Carla Perez-Ingidua, Agustin Gomez de la Camara, Jose Ramon Arribas, Jordi Ochando, Jose Alcami, Cristobal Belda-Iniesta, Jesus Frias · 2021

To date, no immunological data on COVID-19 heterologous vaccination schedules in humans have been reported. We assessed the immunogenicity and reactogenicity of BNT162b2 (Comirnaty, BioNTech, Mainz, G…

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Medicine & Health Peer-Reviewed PDF DOI

A Comparison of the Clinical, Viral, Pathologic, and Immunologic Features of Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and Coronavirus 2019 (COVID-19) Diseases.

Rolf F Barth, L Maximillian Buja, Alison L Barth, David E Carpenter, Anil V Parwani · 2021

-The purpose of this review is to compare three coronavirus diseases: severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and coronavirus disease 2019 (COVID-19) caused …

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Medicine & Health Peer-Reviewed PDF DOI

Post-COVID worsening of a Parkinson's disease patient.

Aliaksandr V Boika, Mikhail M Sialitski, Veranika A Chyzhyk, Vladimir V Ponomarev, Elena G Fomina · 2021

Worsening of clinical symptoms after COVID-19 infection and misregulation of CD4 and CD8 T-cell numbers may be revealed in PD patients. Immunological changes may be a source of clinical worsening of t…

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Medicine & Health Peer-Reviewed PDF DOI

One-year persistence of neutralizing anti-SARS-CoV-2 antibodies in dialysis patients recovered from COVID-19.

Gaetano Alfano, Francesco Fontana, Niccolo Morisi, Francesco Giaroni, Giacomo Mori, Giovanni Guaraldi, Riccardo Magistroni, Gianni Cappelli · 2021

The immunological mechanisms that modulate immune response to SARS-CoV-2 infection remain elusive. Little is known on the magnitude and the durability of antibody response against COVID-19. There is c…

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Medicine & Health Peer-Reviewed PDF DOI

Sex-based clinical and immunological differences in COVID-19.

Bin Huang, Yun Cai, Ning Li, Kening Li, Zhihua Wang, Lu Li, Lingxiang Wu, Mengyan Zhu, Jie Li, Ziyu Wang, Min Wu, Wanlin Li, Wei Wu, Lishen Zhang, Xinyi Xia, Shukui Wang, Hongshan Chen, Qianghu Wang · 2021

Males and females differ in their immunological responses to foreign pathogens. However, most of the current COVID-19 clinical practices and trials do not take the sex factor into consideration. We pe…

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Medicine & Health Peer-Reviewed PDF DOI

Immunological and physiopathological approach of COVID-19 in pregnancy.

Raquel Ferrer-Oliveras, Manel Mendoza, Sira Capote, Laia Pratcorona, Enrique Esteve-Valverde, Lluis Cabero-Roura, Jaume Alijotas-Reig · 2021

Coronavirus disease-2019 (COVID-19) related to Coronavirus-2 (SARS-CoV-2) is a worldwide health concern. Despite the majority of patients will evolve asymptomatic or mild-moderate upper respiratory tr…

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Medicine & Health Peer-Reviewed PDF DOI

Unraveling the Mystery Surrounding Post-Acute Sequelae of COVID-19.

Rakhee K Ramakrishnan, Tarek Kashour, Qutayba Hamid, Rabih Halwani, Imad M Tleyjeh · 2021

More than one year since its emergence, corona virus disease 2019 (COVID-19) is still looming large with a paucity of treatment options. To add to this burden, a sizeable subset of patients who have r…

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Medicine & Health Peer-Reviewed PDF DOI

An Impaired Inflammatory and Innate Immune Response in COVID-19.

Sung Ho Park · 2021

The recent appearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people around the world and caused a global pandemic of coronavirus disease 2019 (COVID-1…

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Medicine & Health Peer-Reviewed PDF DOI

How and to What Extent Immunological Responses to SARS-CoV-2 Shape Pulmonary Function in COVID-19 Patients.

Pierantonio Laveneziana, Christian Straus, Silke Meiners · 2021

COVID-19 is a disease caused by a new coronavirus SARS-CoV-2, primarily impacting the respiratory system. COVID-19 can result in mild illness or serious disease leading to critical illness and require…

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Medicine & Health Peer-Reviewed PDF DOI

Diverse Humoral Immune Responses in Younger and Older Adult COVID-19 Patients.

Jennifer M Sasson, Joseph J Campo, Rebecca M Carpenter, Mary K Young, Arlo Z Randall, Krista Trappl-Kimmons, Amit Oberai, Christopher Hung, Joshua Edgar, Andy A Teng, Jozelyn V Pablo, Xiaowu Liang, Angela Yee, William A Petri, David Camerini · 2021

We sought to discover links between antibody responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and patient clinical variables, cytokine profiles, and antibodies to endemic coro…

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Medicine & Health Peer-Reviewed PDF DOI

Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics.

Adi Nagler, Shelly Kalaora, Chaya Barbolin, Anastasia Gangaev, Steven L C Ketelaars, Michal Alon, Joy Pai, Gil Benedek, Yfat Yahalom-Ronen, Noam Erez, Polina Greenberg, Gal Yagel, Aviyah Peri, Yishai Levin, Ansuman T Satpathy, Erez Bar-Haim, Nir Paran, Pia Kvistborg, Yardena Samuels · 2021

The human leukocyte antigen (HLA)-bound viral antigens serve as an immunological signature that can be selectively recognized by T cells. As viruses evolve by acquiring mutations, it is essential to i…

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Medicine & Health Peer-Reviewed PDF DOI

Predictive factors of smell recovery in a clinical series of 288 coronavirus disease 2019 patients with olfactory dysfunction.

Sven Saussez, Shilpee Sharma, Anais Thiriard, Veronique Olislagers, Ines Vu Duc, Serge-D Le Bon, Mohamad Khalife, Stephane Hans, Giacomo De Riu, Claire Hopkins, Jerome R Lechien, Luigi A Vaira, Arnaud Marchant · 2021

The aim was to evaluate potential predictive factors of smell recovery in a clinical series of 288 patients presenting olfactory dysfunction (OD) related to coronavirus disease 2019 (COVID-19). Potent…

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