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Showing 11725 results for "jonathan bloom" · Peer-Reviewed
Medicine & Health Peer-Reviewed PDF DOI

A New Approach to Bicarbonate Addition During Hemodialysis: Testing Model Predictions in a Patient Cohort

Stefano Marano, Marco Marano, F. John Gennari · 2022

In this study, we present a new protocol for kidney replacement therapy (hemodialysis), based on an explicitly solvable mathematical model. With current protocols, the high and constant level of bath …

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Medicine & Health Peer-Reviewed PDF DOI

Immune thrombocytopenia, severe hematological consequence in a patient with COVID-19: A case report.

Oana-Viola Badulescu, Diana Popescu, Manuela Ciocoiu, Ciprian Rezus · 2021

Since the first appearance of coronavirus disease 2019 (COVID-19), multiple studies have focused on this novel coronavirus. Within a few months, the clinical and paraclinical manifestations and the me…

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Medicine & Health Peer-Reviewed PDF DOI

Omega-3 Index and Clinical Outcomes of Severe COVID-19: Preliminary Results of a Cross-Sectional Study.

Rodrigo Zapata B, Jose Miguel Muller, Juan Enrique Vasquez, Franco Ravera, Gustavo Lago, Eduardo Canon, Daniella Castaneda, Madelaine Pradenas, Muriel Ramirez-Santana · 2021

The potentially detrimental effects of the worldwide deficiency of Omega-3 fatty acids on the COVID-19 pandemic have been underestimated. The Omega-3 Index (O3I), clinical variables, biometric indices…

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Medicine & Health Peer-Reviewed PDF DOI

Diagnostic yield of bacteriological tests and predictors of severe outcome in adult patients with COVID-19 presenting to the emergency department.

Anna Kaal, Lars Snel, Martijn Dane, Nathalie van Burgel, Thomas Ottens, Winifred Broekman, Lahssan El Bouazzaoui, Nikki Kolfschoten, Emile Schippers, Ewout Steyerberg, Soufian Meziyerh, Cees van Nieuwkoop · 2021

Guidelines recommend maximal efforts to obtain blood and sputum cultures in patients with COVID-19, as bacterial coinfection is associated with worse outcomes. The aim of this study was to evaluate th…

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Medicine & Health Peer-Reviewed PDF DOI

Evaluation of Positive End-Expiratory Pressure Strategies in Patients With Coronavirus Disease 2019-Induced Acute Respiratory Distress Syndrome.

Chun Pan, Cong Lu, Xiaobin She, Haibo Ren, Huazhang Wei, Liang Xu, Yingzi Huang, Jia'an Xia, Yuetian Yu, Lu Chen, Bin Du, Haibo Qiu · 2021

Background: Different positive end-expiratory pressure (PEEP) strategies are available for subjects with coronavirus disease 2019 (COVID-19)-induced acute respiratory distress syndrome (ARDS) requirin…

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Medicine & Health Peer-Reviewed PDF DOI

A Clinical Monitoring Program of COVID-19 Outpatients: A Prospective Cohort Study.

Hossein Kasiri, Cyrus Mahjub, Mohammadreza Mazaeri, Fahimeh Naderi-Behdani, Aliyeh Bazi, Monireh Ghazaeian, Sahar Fallah · 2021

Coronavirus disease 2019 (COVID-19) has been associated with a high rate of mortality and morbidity. While a high portion of COVID-19 patients have mild symptoms, a limited number of clinical trials h…

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AI & Data Science Peer-Reviewed PDF DOI

A Rapid and Affordable Point-of-care Test for Detection of SARS-Cov-2-Specific Antibodies Based on Hemagglutination and Artificial Intelligence-Based Image Interpretation.

Hans Haecker, Vanessa Redecke, Kazuki Tawaratsumida, Erin Larragoite, Elizabeth Williams, Vicente Planelles, Adam Spivak, Lincoln Hirayama, Marc Elgort, Shane Swenson, Rick Smith, Bryan Worthen, Russ Zimmerman, Patricia Slev, Ben Cahoon, Mark Astill · 2021

Diagnostic tests that detect antibodies (AB) against SARS-CoV-2 for evaluation of seroprevalence and guidance of health care measures are important tools for managing the COVID-19 pandemic. Current te…

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Medicine & Health Peer-Reviewed PDF DOI

Effect of Canakinumab vs Placebo on Survival Without Invasive Mechanical Ventilation in Patients Hospitalized With Severe COVID-19: A Randomized Clinical Trial.

Roberto Caricchio, Antonio Abbate, Ivan Gordeev, Jamie Meng, Priscilla Y Hsue, Tuhina Neogi, Roberto Arduino, Daria Fomina, Roman Bogdanov, Tatiana Stepanenko, Pilar Ruiz-Seco, Andres Gonzalez-Garcia, Yu Chen, Yuhan Li, Sarah Whelan, Stephanie Noviello · 2021

Effective treatments for patients with severe COVID-19 are needed. To evaluate the efficacy of canakinumab, an anti-interleukin-1β antibody, in patients hospitalized with severe COVID-19. This randomi…

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Medicine & Health Peer-Reviewed PDF DOI

Adversity in early life and pregnancy are immunologically distinct from total life adversity: macrophage-associated phenotypes in women exposed to interpersonal violence.

Kirstin Aschbacher, Melissa Hagan, Iris M Steine, Luisa Rivera, Steve Cole, Alyssa Baccarella, Elissa S Epel, Alicia Lieberman, Nicole R Bush · 2021

Early childhood and pregnancy are two sensitive periods of heightened immune plasticity, when exposure to adversity may disproportionately increase health risks. However, we need deeper phenotyping to…

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Medicine & Health Peer-Reviewed PDF DOI

Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2.

Anu Goenka, Alice Halliday, Michaela Gregorova, Emily Milodowski, Amy Thomas, Maia Kavanagh Williamson, Holly Baum, Elizabeth Oliver, Anna E Long, Lea Knezevic, Alistair J K Williams, Vito Lampasona, Lorenzo Piemonti, Kapil Gupta, Natalie Di Bartolo, Imre Berger, Ashley M Toye, Barry Vipond, Peter Muir, Jolanta Bernatoniene, Mick Bailey, Kathleen M Gillespie, Andrew D Davidson, Linda Wooldridge, Laura Rivino, Adam Finn · 2021

Severe COVID-19 appears rare in children. This is unexpected, especially in young infants, who are vulnerable to severe disease caused by other respiratory viruses. We evaluate convalescent immune res…

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Medicine & Health Peer-Reviewed PDF DOI

Role of Laboratory Medicine in SARS-CoV-2 Diagnostics. Lessons Learned from a Pandemic.

Irena Dus-Ilnicka, Aleksander Szymczak, Malgorzata Malodobra-Mazur, Miron Tokarski · 2021

Since the 2019 novel coronavirus outbreak began in Wuhan, China, diagnostic methods in the field of molecular biology have been developing faster than ever under the vigilant eye of world's research c…

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Medicine & Health Peer-Reviewed PDF DOI

High Seroprevalence of Anti-SARS-CoV-2 Antibodies Among Ethiopian Healthcare Workers.

Tesfaye Gelanew, Berhanu Seyoum, Andargachew Mulu, Adane Mihret, Markos Abebe, Liya Wassie, Baye Gelaw, Abebe Sorsa, Yared Merid, Yilkal Muchie, Zelalem Teklemariam, Bezalem Tesfaye, Mahlet Osman, Gutema Jebessa, Abay Atinafu, Tsegaye Hailu, Antenehe Habte, Dagaga Kenea, Anteneh Gadissa, Desalegn Admasu, Emmet Tesfaye, Timothy A Bates, Jote Bulcha, Rea Tschopp, Dareskedar Tsehay, Kim Mullholand, Rawleigh Howe, Abebe Genetu, Fikadu G Tafesse, Alemseged Abdissa · 2021

Background COVID-19 pandemic has a devastating impact on the economies and health care system of sub-Saharan Africa. Healthcare workers (HWs), the main actors of the health system, are at higher-risk …

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Medicine & Health Peer-Reviewed PDF DOI

Antibody status and cumulative incidence of SARS-CoV-2 infection among adults in three regions of France following the first lockdown and associated risk factors: a multicohort study.

Fabrice Carrat, Xavier de Lamballerie, Delphine Rahib, Helene Blanche, Nathanael Lapidus, Fanny Artaud, Sofiane Kab, Adeline Renuy, Fabien Szabo de Edelenyi, Laurence Meyer, Nathalie Lydie, Marie-Aline Charles, Pierre-Yves Ancel, Florence Jusot, Alexandra Rouquette, Stephane Priet, Paola Mariela Saba Villarroel, Toscane Fourie, Clovis Lusivika-Nzinga, Jerome Nicol, Stephane Legot, Nathalie Druesne-Pecollo, Younes Esseddik, Cindy Lai, Jean-Marie Gagliolo, Jean-Francois Deleuze, Nathalie Bajos, Gianluca Severi, Mathilde Touvier, Marie Zins · 2021

We aimed to estimate the seropositivity to anti-SARS-CoV-2 antibodies in May-June 2020 after the first lockdown period in adults living in three regions in France and to identify the associated risk f…

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Computer Science Peer-Reviewed PDF DOI

Predicting mortality of individual patients with COVID-19: a multicentre Dutch cohort.

Maarten C Ottenhoff, Lucas A Ramos, Wouter Potters, Marcus L F Janssen, Deborah Hubers, Shi Hu, Egill A Fridgeirsson, Dan Pina-Fuentes, Rajat Thomas, Iwan C C van der Horst, Christian Herff, Pieter Kubben, Paul W G Elbers, Henk A Marquering, Max Welling, Suat Simsek, Martijn D de Kruif, Tom Dormans, Lucas M Fleuren, Michiel Schinkel, Peter G Noordzij, Joop P van den Bergh, Caroline E Wyers, David T B Buis, W Joost Wiersinga, Ella H C van den Hout, Auke C Reidinga, Daisy Rusch, Kim C E Sigaloff, Renee A Douma, Lianne de Haan, Niels C Gritters van den Oever, Roger J M W Rennenberg, Guido A van Wingen, Marcel J H Aries, Martijn Beudel · 2021

Develop and validate models that predict mortality of patients diagnosed with COVID-19 admitted to the hospital. Retrospective cohort study. A multicentre cohort across 10 Dutch hospitals including pa…

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Medicine & Health Peer-Reviewed PDF DOI

Incidence and Outcomes of Pulmonary Embolism among Hospitalized COVID-19 Patients.

Omaima Ibrahim Badr, Hassan Alwafi, Wael Aly Elrefaey, Abdallah Y Naser, Mohammed Shabrawishi, Zahra Alsairafi, Fatemah M Alsaleh · 2021

Patients with COVID-19 may be at high risk for thrombotic complications due to excess inflammatory response and stasis of blood flow. This study aims to assess the incidence of pulmonary embolism amon…

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Medicine & Health Peer-Reviewed PDF DOI

Coagulopathy in SARS-CoV-2 Infected Patients: Implication for the Management of COVID-19.

Sisay Getu, Tegenaw Tiruneh, Henok Andualem, Wasihun Hailemichael, Teklehayimanot Kiros, Demeke Mesfin Belay, Mulugeta Kiros · 2021

COVID-19 disease has led to an extraordinary inclusive health crisis globally. Elevation of D-dimer is the major remarkable abnormal coagulation test in seriously ill COVID-19 patients. In nearly 50% …

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Medicine & Health Peer-Reviewed PDF DOI

Methylene Blue has a potent antiviral activity against SARS-CoV-2 and H1N1 influenza virus in the absence of UV-activation in vitro.

Valeria Cagno, Chiara Medaglia, Andreas Cerny, Thomas Cerny, Arnaud Charles-Antoine Zwygart, Erich Cerny, Caroline Tapparel · 2021

Methylene blue is an FDA (Food and Drug Administration) and EMA (European Medicines Agency) approved drug with an excellent safety profile. It displays broad-spectrum virucidal activity in the presenc…

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Medicine & Health Peer-Reviewed PDF DOI

Integrative Modeling of Plasma Metabolic and Lipoprotein Biomarkers of SARS-CoV-2 Infection in Spanish and Australian COVID-19 Patient Cohorts.

Reika Masuda, Samantha Lodge, Philipp Nitschke, Manfred Spraul, Hartmut Schaefer, Sze-How Bong, Torben Kimhofer, Drew Hall, Ruey Leng Loo, Maider Bizkarguenaga, Chiara Bruzzone, Ruben Gil-Redondo, Nieves Embade, Jose M Mato, Elaine Holmes, Julien Wist, Oscar Millet, Jeremy K Nicholson · 2021

Quantitative plasma lipoprotein and metabolite profiles were measured on an autonomous community of the Basque Country (Spain) cohort consisting of hospitalized COVID-19 patients ( n = 72) and a match…

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Medicine & Health Peer-Reviewed PDF DOI

Assessment of severity and mortality of COVID-19 with anti-A1 and anti-B IgM isohaemagglutinins, a reflection of the innate immune status.

Fatih Ozcelik, Alpaslan Tanoglu, Bulent Baris Guven, Umran Keskin, Mustafa Kaplan · 2021

The relationship between the innate immune system that creates the polysaccharide antibody response and COVID-19 is not fully understood. In this study, it was aimed to determine the predictive values…

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Medicine & Health Peer-Reviewed PDF DOI

Efficacy of Intratympanic Glucocorticoid Steroid Administration Therapy as an Initial Treatment for Idiopathic Sudden Sensorineural Hearing Loss During the COVID-19 Pandemic.

Takeshi Tsuda, Yukiko Hanada, Kento Wada, Erina Fujiwara, Kazuya Takeda, Hiroshi Nishimura · 2021

Systemic administration of glucocorticoid steroids is the most common initial treatment for idiopathic sudden sensorineural hearing loss (ISSNHL); however, due to the prevalence of coronavirus disease…

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