Research
Research
Research
Research
15+ open-access research outputs.
We present an adaptive Finite State Projection (FSP) method for efficiently solving the Chemical Master Equation (CME) with rigorous error control. Our approach integrates time-stepping with dynamic s…
Reinforcement learning (RL) has progressed substantially over the past decade, with much of this progress being driven by benchmarks. Many benchmarks are focused on video or board games, and a large n…
Model-free data-driven computational mechanics, first proposed by Kirchdoerfer and Ortiz, replace phenomenological models with numerical simulations based on sample data sets in strain-stress space. I…
Model-free data-driven computational mechanics, first proposed by Kirchdoerfer and Ortiz, replaces phenomenological models with numerical simulations based on sample data sets in strain-stress space. …
Data collected at Hurricane Ian (2022) quantifies the demands that small uncrewed aerial systems (UAS), or drones, place on the network communication infrastructure and identifies gaps in the field. D…
A new relaxation approach is proposed which allows for the description of stress- and strain-softening at finite strains. The model is based on the construction of a convex hull replacing the original…
We develop a hybrid model-based data-driven seizure detection algorithm called Mutual Information-based CNNAided Learned factor graphs (MICAL) for detection of eclectic seizures from EEG signals. Our …
The data-driven computing paradigm initially introduced by Kirchdoerfer and Ortiz (2016) enables finite element computations in solid mechanics to be performed directly from material data sets, withou…
The data-driven computing paradigm initially introduced by Kirchdoerfer & Ortiz (2016) is extended by incorporating locally linear tangent spaces into the data set. These tangent spaces are constructe…
Automated chemical synthesis carries great promises of safety, efficiency and reproducibility for both research and industry laboratories. Current approaches are based on specifically-designed automat…
We extend the Data-Driven formulation of problems in elasticity of Kirchdoerfer and Ortiz (2016) to inelasticity. This extension differs fundamentally from Data-Driven problems in elasticity in that t…
The capacity to predict and control bioprocesses is perhaps one of the most important objectives of biotechnology. Computational simulation is an established methodology for the design and optimizatio…
When designing genetic circuits, the typical primitives used in major existing modelling formalisms are gene interaction graphs, where edges between genes denote either an activation or inhibition rel…
In this paper we propose a model-order reduction method for chemical reaction networks governed by general enzyme kinetics, including the mass-action and Michaelis-Menten kinetics. The model-order red…
BACKGROUND: Labyrinthine Aplasia, Microtia and Microdontia (LAMM) syndrome is characterized by the complete absence of inner ear structures (Michel aplasia), microtia and microdontia. Hypophosphatemic…
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