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🔍 tom rainforth 📂 Computer Science 📄 Peer-Reviewed
Showing 219 results for "tom rainforth" in Computer Science · Peer-Reviewed
Computer Science Peer-Reviewed PDF DOI

A Novel Computational Approach for the Discovery of Drug Delivery System Candidates for COVID-19.

Taeheum Cho, Hyo-Sang Han, Junhyuk Jeong, Eun-Mi Park, Kyu-Sik Shim · 2021

In order to treat Coronavirus Disease 2019 (COVID-19), we predicted and implemented a drug delivery system (DDS) that can provide stable drug delivery through a computational approach including a clus…

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Computer Science Peer-Reviewed PDF DOI

A meta-analysis for Lianhua Qingwen on the treatment of Coronavirus disease 2019 (COVID-19).

Jieqin Zhuang, Xingzhen Dai, Qihua Wu, Hairong Cai, Xue Fu, Weizhang Zhang, Bojun Chen · 2021

Traditional Chinese medicine (TCM) has been proven to played a great important role on the treatment of COVID-19. As one of the drugs recommended in Chinese guidelines, Lianhua Qingwen Granules or Cap…

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Computer Science Peer-Reviewed PDF DOI

Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and other viral infections: Efficacies and mechanisms.

Kai Huang, Pan Zhang, Zhenghao Zhang, Ji Youn Youn, Chen Wang, Hongchun Zhang, Hua Cai · 2021

COVID-19 has remained an uncontained, worldwide pandemic. While battling for the disease in China, six Traditional Chinese Medicine (TCM) recipes have been shown to be remarkably effective for treatin…

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Computer Science Peer-Reviewed PDF DOI

Characteristics of systematic reviews evaluating treatments for COVID-19 registered in PROSPERO.

Ruinian Zhang, Ya Gao, Dairong Xie, Rongna Lian, Jinhui Tian · 2021

Characteristics and research collaboration of registered systematic reviews (SRs) on treatment modalities for coronavirus disease-2019 (COVID-19) remain unclear. This study analysed research collabora…

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Computer Science Peer-Reviewed PDF DOI

Carbapenem-Resistant Infections in ICU COVID-19 Patients-A Scoping Review.

Wioletta Medrzycka-Dabrowska, Sandra Lange, Katarzyna Zorena, Sebastian Dabrowski, Dorota Ozga, Lucyna Tomaszek · 2021

The spread of multidrug-resistant pathogens is a serious problem and challenge for the whole medical community. Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections in immunocompromised patien…

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Computer Science Peer-Reviewed PDF DOI

Efficacy and safety of Reyanning mixture combined with conventional Western medicine for treating COVID-19: A protocol for systematic review and meta-analysis.

Yajuan Li, Jingxia Zhang, Shasha Li, Fan Li, Chongbo Zhao, Fang Li, Weifeng Wang, Wei Wang · 2021

Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a pandemic affecting nearly…

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Computer Science Peer-Reviewed PDF DOI

Traditional Chinese Medicine as a complementary therapy in combat with COVID-19-A review of evidence-based research and clinical practice.

Xi Vivien Wu, Yanhong Dong, Yuchen Chi, Mingming Yu, Wenru Wang · 2021

To examine the literature on Traditional Chinese Medicine (TCM) used in the treatment, prevention and supportive care in patients with COVID-19. A narrative review was performed. A systematic and comp…

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Computer Science Peer-Reviewed PDF DOI

Similarity and Specificity of Traditional Chinese Medicine Formulas for Management of Coronavirus Disease 2019 and Rheumatoid Arthritis.

Zheng Li, Hongwei Chen, Huixia Zhang, Yan Li, Caiyun Wang, Liping Bai, Wei Zhang, Zhihong Jiang · 2021

The pathogenesis similarity is leading to the introduction of drugs commonly used in rheumatoid arthritis (RA) into coronavirus disease (COVID-19) treatment. Traditional Chinese medicine (TCM) was wid…

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Computer Science Peer-Reviewed PDF DOI

Toward a Better Understanding of the Intention to Use mHealth Apps: Exploratory Study.

Pedro R Palos-Sanchez, Jose Ramon Saura, Miguel Angel Rios Martin, Mariano Aguayo-Camacho · 2021

An increasing number of mobile health (mHealth) apps are becoming available for download and use on mobile devices. Even with the increase in availability and use of mHealth apps, there has still not …

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Computer Science Peer-Reviewed PDF DOI

Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease.

Chandrabose Selvaraj, Umesh Panwar, Dhurvas Chandrasekaran Dinesh, Evzen Boura, Poonam Singh, Vikash Kumar Dubey, Sanjeev Kumar Singh · 2021

The recent pandemic outbreak of COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), raised global health and economic concerns. Phylogenetically, SARS-CoV-2 is closely re…

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Computer Science Peer-Reviewed PDF DOI

In silico analysis of the potential mechanism of a preventive Chinese medicine formula on coronavirus disease 2019.

Huaying Wu, Ke Gong, You Qin, Zhiying Yuan, Shuaishuai Xia, Shiying Zhang, Jingjing Yang, Ping Yang, Liang Li, Mengzhou Xie · 2021

With the spread of Coronavirus Disease (2019) (COVID-19), combination with traditional Chinese medicine (TCM) has been widely used as a prevention and therapy strategy in China. Xin guan No.1 (XG-1) p…

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Computer Science Peer-Reviewed PDF DOI

Unusual zwitterionic catalytic site of SARS-CoV-2 main protease revealed by neutron crystallography.

Daniel W Kneller, Gwyndalyn Phillips, Kevin L Weiss, Swati Pant, Qiu Zhang, Hugh M O'Neill, Leighton Coates, Andrey Kovalevsky · 2021

The main protease (3CL M pro ) from SARS-CoV-2, the etiological agent of COVID-19, is an essential enzyme for viral replication. 3CL M pro possesses an unusual catalytic dyad composed of Cys 145 and H…

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Computer Science Peer-Reviewed PDF DOI

Network pharmacology analysis of the therapeutic mechanisms of the traditional Chinese herbal formula Lian Hua Qing Wen in Corona virus disease 2019 (COVID-19), gives fundamental support to the clinical use of LHQW.

Shichao Zheng, Jan P Baak, Shuang Li, Wenke Xiao, Hong Ren, Huan Yang, Yanxiong Gan, Chuanbiao Wen · 2021

The traditional Chinese Medicine (TCM) herbal formula Lian Hua Qing Wen (LHQW) improves the results of COVID-19 treatment. Three very recent studies analyzed with network pharmacology some working mec…

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Computer Science Peer-Reviewed PDF DOI

Epigallocatechin-3-gallate, an active ingredient of Traditional Chinese Medicines, inhibits the 3CLpro activity of SARS-CoV-2.

Ashuai Du, Rong Zheng, Cyrollah Disoma, Shiqin Li, Zongpeng Chen, Sijia Li, Pinjia Liu, Yuzheng Zhou, Yilun Shen, Sixu Liu, Yongxing Zhang, Zijun Dong, Qinglong Yang, Moyed Alsaadawe, Aroona Razzaq, Yuyang Peng, Xuan Chen, Liqiang Hu, Jian Peng, Qianjun Zhang, Taijiao Jiang, Long Mo, Shanni Li, Zanxian Xia · 2021

SARS-CoV-2 is the etiological agent responsible for the ongoing pandemic of coronavirus disease 2019 (COVID-19). The main protease of SARS-CoV-2, 3CLpro, is an attractive target for antiviral inhibito…

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Computer Science Peer-Reviewed PDF DOI

Use of traditional Chinese medicine as an adjunctive treatment for COVID-19: A systematic review and meta-analysis.

Feng Li, Yongqing Jiang, Bei Yue, Lili Luan · 2021

This review aims to evaluate the supportive effects of frequently used traditional Chinese medicine (TCM) for the treatment of coronavirus disease 2019 (COVID-19). Five databases were searched through…

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Computer Science Peer-Reviewed PDF DOI

Efficacy and Safety of Traditional Chinese Medicine in Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis.

Heping Wang, Bowen Xu, Ying Zhang, Yuanyuan Duan, Ruike Gao, Haoqiang He, Xiuyang Li, Jie Li · 2021

Introduction: Until now, there is no clinically approved specific medicine to treat COVID-19. Prior systematic reviews (SRs) have shown that traditional Chinese medicine (TCM) reduces the number of pa…

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Computer Science Peer-Reviewed PDF DOI

Investigating the active compounds and mechanism of HuaShi XuanFei formula for prevention and treatment of COVID-19 based on network pharmacology and molecular docking analysis.

Juan Wang, Wen Ge, Xin Peng, Lixia Yuan, Shuaibing He, Xuyan Fu · 2021

Traditional Chinese medicine (TCM) has exerted positive effects in controlling the COVID-19 pandemic. HuaShi XuanFei Formula (HSXFF) was developed to treat patients with mild and general COVID-19 in Z…

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Computer Science Peer-Reviewed PDF DOI

Simultaneous Inhibition of SARS-CoV-2 Entry Pathways by Cyclosporine.

Kartikay Prasad, Shahzaib Ahamad, Hema Kanipakam, Dinesh Gupta, Vijay Kumar · 2021

The COVID-19 pandemic caused by SARS-CoV-2 represents a global public health emergency. The entry of SARS-CoV-2 into host cells requires the activation of its spike protein by host cell proteases. The…

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Computer Science Peer-Reviewed PDF DOI

The efficacy and safety of Jinhua Qinggan granule (JHQG) in the treatment of coronavirus disease 2019 (COVID-19): A protocol for systematic review and meta analysis.

Qiongshuai Zhang, Fang Cao, Yufeng Wang, Xiaohong Xu, Yihan Sun, Jiannan Li, Xun Qi, Shaoqian Sun, Guangcheng Ji, Bailin Song · 2021

Currently, the global number of infected novel coronavirus has exceeded 2.6 million and the death toll has exceeded 170,000, but the specific drug for the treatment of COVID-19 has been not appears. I…

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Computer Science Peer-Reviewed PDF DOI

Identification of high-affinity inhibitors of SARS-CoV-2 main protease: Towards the development of effective COVID-19 therapy.

Taj Mohammad, Anas Shamsi, Saleha Anwar, Mohd Umair, Afzal Hussain, Md Tabish Rehman, Mohamed F AlAjmi, Asimul Islam, Md Imtaiyaz Hassan · 2021

Coronavirus disease 2019 (COVID-19) is an infectious disease, caused by a newly emerged highly pathogenic virus called novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Targeting the…

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